منابع مشابه
AAA+ Molecular Machines: Firing on All Cylinders
The AAA+ ATPase motif is found in proteins from all kingdoms of life. The cellular roles of these proteins are diverse; hence the AAA+ designation for ATPase’s associated with various cellular activities. Many of these enzymes act as machines, using energy generated from the binding and hydrolysis of ATP to remodel a variety of macromolecular assemblies in the cell [1]. For example, AAA+ subuni...
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The incidence of oxygen desaturation (less than 91%) was measured by pulse oximetry during recovery from outpatient dental anaesthesia in 120 ASA grade I and II children. Alternate cases were given supplementary oxygen 5 litre min-1 by mask. Eighteen of 60 children (30%) given air and 14 of 60 (23%) given oxygen exhibited desaturation (P greater than 0.05). Desaturation was more likely to occur...
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Twelve dogs were anaesthetized with halothane and allowed to breathe spontaneously gas comprising either 100 per cent oxygen at 2 ATA (the test group) or 40 per cent oxygen/60 per cent nitrogen at 1 ATA (the control group). The control group survived to 24 hours without undergoing any significant change in cardiac output, pulmonary shunt ratio or A-a Po2 difference. The test group of animals di...
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FOLLOWING experimental work on animals it has been suggested that the effectiveness of X-ray treatment of tumours may be increased by the simultaneous administration of oxygen under high pressure (Gray et al., 1953). To determine if these results were applicable to be made much more radiosensitive by increasing the oxygen tension. Many tumours, however, contain large numbers of cells which, bec...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1991
ISSN: 0007-0912
DOI: 10.1093/bja/66.5.628-a